ω-6 and ω-3 polyunsaturated fatty acids play an important role in organisms, the two groups of polyunsaturated fatty acids function coordination, jointly regulate the life activity of organisms, but they use the same metabolism of carbon chain elongase and desaturase, competitive inhibition between ω-3 and ω-6 PUS fatty acids in a competitive relationship, to use the same enzyme catalysis, so the balance in the body content is particularly important.

The healthy ratio of omega-6 to omega-3 ranged from 1:1 to 2:1, and people consume equal intake of both fats.However, it was shown that modern dietary habits lead to a western diet containing higher levels of omega-6, ratio between 10:1 and 20:1.2 compared to omega-3

Studies have shown that excess omega-6 polyunsaturated fatty acids (PUFAs) and very high proportions of omega-6 to omega-3 can contribute to the onset of many diseases, including cancer, cardiovascular disease (CVD), inflammation, and autoimmune diseases.At the same time, increased omega-3 levels (the low ratio of omega-6 to omega-3) can produce inhibitory effects.These findings suggest that it is necessary for individuals to adjust their diet to resolve the omega-6 to omega-3 imbalance.